DOI: 10.36347/sajb.2013.v01i01.003

Pages: 14-17

Abstract: The objective of the study is to compare the noninvasive tests (antigen and antibody dectection) for identification of Helicobacter pylori. (H.pylori). A total of 81 serum and stool specimens were collected from out patients and in patients presenting with upper gastrointestinal symptoms of both the sexes in age group of 20-70 over a period of 12 months from tertiary care hospital. Of 81 biopsy specimen, 59 were male (72.4%) and 22(27.6%) female, and the maximum number of patients was in the age group 40-49. The endoscopy results revealed that duodenal ulcer accounted for 36%, gastritis in 30%, gastric carcinoma in 16%, and gastric ulcer in 17%. In the present study stool specimens and serum samples were subjected to examination for detection of Antigen and Antibody respectively. Antibody was detected in 29 out of the 81 samples tested (35.8%) whereas Stool Antigen was positive in 23 (28.40%) out of 81 samples tested. Majority of cases were in the age group of 40-49 years of male preponderance. The present study reveals that serology showed a slightly greater number of positive cases.