DOI: 10.36347/sjams.2014.v02i03.031

Pages: 1028-1032

Cystatin C, an established marker of renal dysfunction, is gaining importance in dysfunction of other organs (systems) as well. Preliminary studies indicated a role for cystatin C as a prognostic marker in coronary artery disease (CAD). The aim of the study was to assess the of serum cystatin C levels in CAD cases and its comparison with controls. Comparison of serum cystatin C levels in CAD spectrum. Comparison of serum cystatin C levels in CAD cases based on risk factors,body mass index (BMI) and waist circumferance(WC).cystatin C levels in CAD cases based on risk factors,body mass index (BMI) and waist circumferance(WC). Study group comprised of 145 patients diagnosed as having CAD based on clinical and bio-chemical criteria. Control group included 66 age and sex matched subjects (non CAD cases) using the above mentioned criteria. In this study, significant increase of mean serum cystatin C levels was observed in CAD cases than controls. Highest mean cystatin C values were observed in Myocardial infarction (MI) than Unstable angina (UA) and Stable angina (SA).Highest mean cystatin C values were CAD cases with risk factors. Highest mean cystatin C values were CAD with increased BMI and WC. Cystatin C plays an important role in the development of CAD and serum cystatin C is a might have a role as a prognostic marker in patients with CAD.