DOI: 10.36347/sjams.2014.v02i03.040

Pages: 1075-1080

Coronary artery disease is progressively assuming an alarming proportion as a cause of morbidity and mortality in India and other developing countries in South Asia. There are a number of studies on coronary risk factors in Indian subcontinent, mostly in urban population, which pointed to differences in the prevalence of the risk factors in different geographical territories of the country. There was no such community-based study in rural population of Bihar. Hence this case control study was undertaken to evaluate the important biochemical risk factors for rural patients admitted to hospital with acute myocardial infarction. 100 consecutive cases of first attack of AMI aged 30 to 90 years were compared to 50 ages and sex matched healthy controls. Age, gender, blood pressure, history of smoking and diabetes mellitus, waist-hip ratio and Body Mass Index were recorded in each subject. Blood samples for fasting blood glucose, HbA1C, serum cholesterol, triglyceride, HDL–cholesterol and LDL-cholesterol were collected within 24 hours of admission in cases. It was found that high FBG, HbA1c, TG, low HDL cholesterol were significant in all the age groups above 40 years. Smoking, hypertension, abdominal obesity were important risk factors for AMI in our study. Interestingly our study is not associated with increased risk of AMI with either cholesterol or LDL levels. . In order to implement preventive approach to CAD, our findings suggest that policy makers, physicians and non government organizations and public must work together and develop risk reduction strategies that focus on promoting healthier lifestyles in the rural communities.