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Scholars Journal of Applied Medical Sciences | Volume-2 | Issue-04
Clinical Trial of A Polyherbal Preparation (Tefroliv – Forte) In Patients With Chronic Hepatitis B
Appandraj S, Dinakaran N
Published: July 29, 2014 | 147 105
DOI: 10.36347/sjams.2014.v02i04.020
Pages: 1263-1266
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Abstract
Hepatitis B infection is known to be a common cause of cirrhosis and hepatocellular carcinoma world wide. Though many drugs are being tried to slow down the progression of the disease, a safe, effective and universally acceptable therapy is still elusive. This study analyses the effectiveness of a polyherbal formulation in chronic hepatitis B infection. The study was conducted in 45 patients, of age group 18 to 62 years with duration of 6 months treatment. Symptomatic patients with HbsAg Positivity persistent for more than 6 months were included. Patients were given a poly herbal preparation 2 tablets 3 times a day for a period of 6 months. Seroconversion of 31% of HbsAg positivity, 42% in Anti HbcAb, 41% in HbeAg and 100% of anti HbeAb. Therapy with polyherbal preparation used by us in chronic hepatitis B infection was found to be effective and safe. No clinical deterioration observed during study period.