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Scholars Journal of Applied Medical Sciences | Volume-2 | Issue-05
Comparative Study of Significance of Lipid Profile, Platelet Count and MPV-Diabetics and Non-Diabetics
Vijaya C, Archana Shetty, Parikshith
Published: Sept. 27, 2014 |
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159
DOI: 10.36347/sjams.2014.v02i05.016
Pages: 1584-1588
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Abstract
Diabetes mellitus is a global pandemic and is a complex disease characterized by chronic hyperglycaemia,
metabolic abnormalities and long term macro – vascular and microvascular abnormalities involving major organs.
Platelet parameters such as high platelet count and mainly high Mean Platelet Volume (MPV) have been reported in
diabetic patients, contributing to the increased risk of vascular disease. Its relation to lipid profile has also been
documented in literature. The objective of our study is to compare the simple variables of platelet count, MPV, and lipid
profiles in normoglycemics and in diabetics. This cross sectional study was conducted at Sapthagri Institute of Medical
Sciences and Research Center, Bangalore, India between the periods of December 2013 to March 2104. A total of 100
cases were included with 50 being diabetics and other 50 being non – diabetics. The study documented a significant
increase in total cholesterol and LDL (females>males) in diabetics. Triglycerides and VLDL (males>females) in were
more in diabetics compared to the normoglycemics. Platelet count has increased more significantly in diabetic females
than males and control group.MPV has increased more significantly in diabetic males than females and control group.
Simple parameters like above can be used to screen patients at high risk for complications, aiding in better patient care.