DOI: 10.36347/sjams.2014.v02i05.055

Pages: 1765-1767

The naturally occurring fluctuations in the levels of sex steroid hormones during the menstrual cycle provide a convenient basis for analyzing the interactions between sex steroid hormones and immune mechanisms. The study includes the estimation of differential leucocyte count (DLC) in different phases of menstrual cycle. The aim was to study if there are variations in differential leukocyte count in three phases of menstrual cycle. The study comprised of 100 girls between the age group of 18-25 yrs. 2ml venous blood sample were collected under aseptic precautions during a single cycle in three different phases of their menstrual cycle on 2nd day of menstrual cycle, 11th day and 21st day that is menstrual phase (MP), proliferative phase (PP) and secretory phase (SP) respectively. Assessment of differential leucocyte count (DLC) was done using automated analyzer. Significant changes were observed in DLC, during the three phases of menstrual cycle and more so during the secretory phase of menstrual cycle which is probably due to the hormonal changes during the luteal phase. The study of eukocyte counts during the menstrual cycle had indicated that there were cyclical fluctuations in the differential leukocyte count over the course.