DOI: 10.36347/sjams.2014.v02i06.044

Pages: 3057-3059

Chronic renal failure is one of the most commonly encountered diseases in the hospital. Chronic renal failure (CRF) is a term used to describe gradual reduction in renal function over the span of weeks to years. Therapeutic options include Hemodialysis (HD), peritoneal dialysis (PD) and transplantation. Anaphylactic reactions related to hemodialysis have been increasingly described for almost 3 decades. The majority of these cases used to occur with ethylene oxide and with sterilized, complement activated cellulose membrane. Chronic renal failure patients who are on hemodialysis are observed for the prevalence of dialyzer reactions. Signs of a hypersensitivity reaction generally appear within few minutes after exposure to the provoking agent. Immune effector cells are often involved, with or without IgE involvement, but reactions may also show non-immune mediated mechanisms.