DOI: 10.36347/sjams.2014.v02i06.066

Pages: 3176-3184

Malaria is a mosquito borne parasitic disease caused by the bite of female Anopheles mosquito. Globally it affects the tropics and sub-tropics. It is endemic in Khammam district of Andhra Pradesh. Out of the four Plasmodium species, P. falciparum is the leading cause of complications due to capillary infarcts, leakage and organ dysfunction. The study aims to study the incidence of complications of malaria and to study the response to treatment in complicated malaria. The study was conducted at Mamata General Hospital, Khammam. A total number of 50 patients who are proved “smear positive” and card test positive for P. falciparum are studied during the period of January 2013 to February 2014 All patients > 12 years who had a positive blood smear and rapid diagnostic test (card test) for Falciparum malaria in Mamata General Hospital, Khammam were included. Exclusion criteria include age <12 years patients, only gametocyte of PF, P. vivax smear positive and mixed smear positive, diagnosed cases of Malaria without complications. The most common complication as per our study is anemia, seen in 82% of cases, followed by jaundice (64%), respiratory distress (20%), cerebral malaria (18%), bleeding disorders (18%), ARF (12%), hypoglycaemia (6%), and there is good response to treatment with artemesinin combination therapy. 1 patient died due to multiple organ dysfunction.