DOI: 10.36347/sjams.2014.v02i06.112

Pages: 3404-3408

Metabolic syndrome in obese adolescents continues until adulthood. Metabolic syndrome comprises of components, which are the risk factor for coronary heart disease, type II diabetes mellitus and renal failure. Several studies have demonstrated a close relationship between metabolic syndrome and hyperuricemia. There is limited studies on association between metabolic syndrome and hyperuricemia in adolescents in Indonesia. The aim of this study were to determine the prevalence of metabolic syndrome and hyperuricemia in Minahasa obese adolescents population. This study was a cross-sectional design conducted in senior high school students population in February 2013, involving a total of 160 obese students including 54 males and 106 females, aged 13-18 years. Antopometric measurements including height measurement (HM), body weight (BW), waist circumference (WC) and blood pressure and laboratory tests such as lipid profile, plasma glucose level and uric acid levels. Determination of metabolic syndrome using the IDF criteria, 2007. The participants had to meet ≥ 3 following criteria: WC ≥90 cm for male and ≥ 80 cm for female, triglyceride levels ≥150 mg/dl, male HDL <40 mg/dl,female <50 mg/dl, blood pressure ≥130/85 mmHg, and fasting blood glucose ≥100 mg/dl. Data analyzed using univariate, bivariate and Pearson correlation test. The prevalence of metabolic syndrome within obese adolescents was 41.9%,and more than 55.6% has hyperuricemia. Components of the metabolic syndrome that significantly associated with hyperuricemia; WC, triglycerides and systolic blood pressure (p = <0.05). Over 40% obese adolescent in Minahasa had metabolic syndrome and more than 50% had hyperuricemia. The results of this study provides evidence for prevention against the risk of degenerative diseases morbidity and management among obese adolescents.