DOI: 10.36347/sjams.2014.v02i06.125

Pages: 3471-3474

Background:Pre-eclampsia is defined as the onset of hypertension after mid-pregnancy; a systemic disease of the later stages of pregnancy that affects about 5 - 7% of all pregnancies and is the most common. Typically, blood pressure elevations and pre-eclampsia occur in the late second or third trimesters and gestational outcome is hardly affected. Material and Methods: This is perspective and observational study conducted in the Department of Biochemistry in association of Department of General Medicine over a period of six months. In this study investigation was done to determine the contribution of different biochemical parameters of females suffering from preeclampsia and Eclampsia. The study was carried out on Case group - 60 pre-eclampsia and eclampsia patients compare to Control group - 60 normal pregnant females. Selection criteria; Control: Normal pregnant females randomly selected from the hospital who is not suffering from any other medical disorder. Cases: All the patients of preeclampsia and Eclampsia will be admitted in the hospital. Results:The systolic blood pressure in case group was 171.3 ± 5.1 mmHg and control group 129.4 ± 5.2 mmHg. On the other hand, diastolic blood pressure in case group was 98.54 ± 4.3 mmHg and control group 79.59 ± 4.7 mmHg. Oxidative marker between Case and control group was statistically significantly difference. MDA in case group was 3.01 ± 0.41nmol/mL and Control 1.61 ± 0.32 nmol/mL.Antioxidant marker between Case and control group wasstatistically significantly difference.