DOI: 10.36347/sjams.2017.v05i02.032

Pages: 465-469

Growing incidence of Breast cancer is seen especially in young women and greater numbers of women are likely to consult for breast masses with increasing awareness about breast cancer. With this background we tried to evaluate the Sensitivity and Specificity of Fine-needle aspiration biopsy when compared with Histopathology in diagnosis of Breast lesions. This study was conducted in Chalmeda Anandarao Institute of Medical Sciences [CAIMS] Karimnagar. FNAC was performed in all suspected breast masses using 23 Gauge Needle attached to 20 ml disposable syringe. Smear was prepared on standard glass slides fixed and stained with Haematoxyline and Eosin stain. The cases were reported using 5 tier system C1-C5. Histopathology examination of the same was also done to confirm the diagnosis. 88 patients were studied in this process age ranging from 35 to 60 years, the cases were reported using a 5 tier system C1 for inadequate; C2 for benign; C3 for suspicious probably benign; C4 for suspicious probable malignant and C5 for malignant lesions. Out of (n=88) C1 were (n=1) 1.14%, C2 were (n=45) 51.13%, C3 were (n=22) 44%, C4 (n=13) 14.77% and C5 (n=7) 7.9%. Out these 88 samples by histopathology (n=67) 76.13% were found to be Benign and (n=21) 23.86%. Sensitivity was 87.5% CI= 67.64% to 97.34%, Specificity was 97.1% CI= 89.92% to 99.65%. FNAC is a rapid relatively painless and low cost and acceptable procedure that can be done on out-patient basis. It can be done on both superficial as well as difficult located lesions. The overall sensitivity, specificity and predictive values are within acceptable range provided standard procedures are adopted.