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Scholars Journal of Applied Medical Sciences | Volume-5 | Issue-02
A Study of Predictive Factors Affecting Outcome of Intrauterine Tuboperitoneal Insemination
Verma Asha, Gupta Disha, Gupta Richa, Bansal Shikha, Jain Nikita, Jain Baishali
Published: Feb. 28, 2017 |
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144
DOI: 10.36347/sjams.2017.v05i02.052
Pages: 566-569
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Abstract
Infertility management has become more substantial and relevant with an increase in the number of infertile
patients as well as advances in the science of reproduction. The objective of our study was to assess the factors predicting
the treatment outcome of a new assisted reproductive technique, intrauterine tuboperitoneal insemination (IUTPI) in the
treatment of infertile patients. 118 cases, after applying both inclusion and exclusion criteria were enrolled in the study.
Patients were given clomiphene citrate for ovarian stimulation followed by injection human chorionic gonadotropin for
triggering ovulation. Insemination was then performed with washed husband’s sperm after about 36-40 hours, using
10ml of inseminate. The patient was then called after 2 weeks for urine pregnancy test which, if positive was considered
as clinical pregnancy. Out of 118 cases, 27 cases were positive. The pregnancy rate was 22.88%. Endometrial thickness,
preovulatory follicle number, prewash sperm motility and post wash sperm motility significantly affected the pregnancy
outcome. Factors like patient’s age, BMI<25, bilateral patent tubes and decreased duration of infertility also positively
affected the outcome. IUTPI may, thus, become an attractive first line option for infertile couples, considering cost
benefits over in vitro fertilization and significantly better pregnancy rate over intrauterine insemination. A knowledge of
predictive factors may be of help to offer and counsel patients regarding success of treatment outcome in IUTPI.