DOI: 10.36347/sjams.2017.v05i02.068

Pages: 643-650

Quality in laboratory has huge impact on diagnosis and patient management as about 80% of all diagnosis is made on the basis of laboratory tests. The clinical measurement of C-reactive protein( CRP) in serum , therefore appears to be a valuable screening test for organic disease and a sensitive index of disease activity in inflammatory, infective and ischaemic conditions. Accurate result of CRP values is important to accurately predict the difference between viral and bacterial infections and also in predicting whether the patient is responding to antimicrobial therapy among others and therefore the need for its accurate reporting. This prospective study was carried out in Shaheed Hasan Khan Mewati, GMC College, A tertiary care centre from the period September 2015 to April 2016 for a period of six months to estimate accuracy of semi-Quantitative results of CRP testing and to improve the accuracy of CRP semi-quantitative screening by using six sigma techniques, if needed. The entire process was divided into Define, Measure, Analyze phase followed by suggestions for improvement for improving accuracy . 41 consecutive readings of CRP positive control by 2 operators was recorded as with a standard deviation of 3.86 with a mean of 6.21. cpk was calculated as 0.26. Since it was less than 1 , hence The process did not meet its specification. Further there were approximately 390243 DPMO and hence the process was at less than 2 sigma level or approximately at 1.6 sigma equivalent.