DOI: 10.36347/sjmcr.2020.v08i04.001

Pages: 427-430

We report four cases of exophthalmos related to malignant lymphoma, highlighting the value of surgical biopsy. These were four patients aged 33, 50, 55 and 62 respectively. Unilateral exophthalmos was the reason for consultation in all cases. The diagnosis of non-Hodgkin's lymphoma was suspected by imaging and confirmed by pathological examination of surgical biopsies. It was type B lymphoma in 3 cases and TNK type lymphoma in 1 case. They all benefited from polychemotherapy. The evolution was marked by the regression of the tumor and exophthalmos. These cases show that the clinical polymorphism of malignant lymphomas is extreme. They can cause diagnostic problems and delay treatment. Hence the interest of the histological examination of a tissue biopsy.