DOI: 10.36347/sjmcr.2014.v02i08.008

Pages: 526-529

Mesenchymal chondrosarcoma is a rare aggressive variant of chondrosarcoma that frequently occurs in extra skeletal location and has high predilection for the head and neck region. In our case report a 30 years old lady presented with pain and rapidly growing swelling over lower lateral part of the left leg. The biopsy revealed mesenchymal chondrosarcoma of fibula composed of highly undifferentiated small round cells and islands of well differentiated cartilage involving both the bony tissue as well as soft tissue. Report of immunohistochemistry also supported our diagnosis. Here we report a rare entity that should be considered in the differential diagnosis of any calcified bony lesions, especially in young adults. Since this tumour has a high tendency of metastasis mainly to the lungs, the prognosis is worse in relation to conventional chondrosarcoma. The patient was given a course of adjuvant chemotherapy following complete removal of the tumour but the patient died within one year of follow up.