DOI: 10.36347/sjmcr.2020.v08i04.021

Pages: 492-495

Introduction: Dubin and Johnson syndrome (DJS) is autosomal recessive, inherited disorder with no progression to end-stage Liver disease.it result in mainly unconjugated hyper bilirubinaemia. Clinical onset of DJS often begin during the teenage years or in early adulthood. There are case reports describe the coincidence of DJS and colon cancer. Brief case report: We describe 27 years old male diagnosed with adenocarcinoma of the colon few years after the clinical onset of DJS. Conclusion: Attention should be taken when evaluating a young adult with DJS and be aware of this risk and consequences of a late diagnosis of colorectal cancer.