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Scholars Journal of Medical Case Reports | Volume-2 | Issue-11
Leiomyosarcoma of Transverse Colon: A Rare Presentation
Rajendra Prasad Bugalia, Anuradha Salvi, Dhananjay Saxena, Prashant Garg, Raj Kamal Jenaw, Vipul Agarwal, Jeevan Kankaria
Published: Nov. 30, 2014 |
112
80
DOI: 10.36347/sjmcr.2014.v02i11.014
Pages: 739-742
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Abstract
Leiomyosarcoma (LMS) of the gastrointestinal tract is an extremely rare high-grade neoplasm with poor
prognosis. Leiomyosacromais is an uncommon malignant tumor which arises from a variety of sites including the
gastrointestinal tract, genitourinary tract, retro peritoneum, superficial soft tissue, lungs and inferior vena cava. The
transverse colon is extremely rare site for a primary leiomyosarcoma. This patient presented to our department with
abdominal lump. Neither physical signs nor any investigation could ascertain its diagnosis and origin; only surgery and
immunohistochemistry revealed this extremely rare tumor. Total excision followed by chemotherapy was curative.LMS
frequently metastasize to liver and has poor prognosis. Unlike gastrointestinal stromal tumors (GIST) effective molecular
therapy is not available for LMS. Thus, the decision regarding the selection of an optimal therapeutic strategy for
advanced LMS with metastasis is difficult. Here we present an unusual case of LMS of the transverse colon with liver
metastasis. The survival of this patient was prolonged by a combined modality therapy involving surgery and
chemotherapy.