DOI: 10.36347/sjmcr.2014.v02i11.014

Pages: 739-742

Leiomyosarcoma (LMS) of the gastrointestinal tract is an extremely rare high-grade neoplasm with poor prognosis. Leiomyosacromais is an uncommon malignant tumor which arises from a variety of sites including the gastrointestinal tract, genitourinary tract, retro peritoneum, superficial soft tissue, lungs and inferior vena cava. The transverse colon is extremely rare site for a primary leiomyosarcoma. This patient presented to our department with abdominal lump. Neither physical signs nor any investigation could ascertain its diagnosis and origin; only surgery and immunohistochemistry revealed this extremely rare tumor. Total excision followed by chemotherapy was curative.LMS frequently metastasize to liver and has poor prognosis. Unlike gastrointestinal stromal tumors (GIST) effective molecular therapy is not available for LMS. Thus, the decision regarding the selection of an optimal therapeutic strategy for advanced LMS with metastasis is difficult. Here we present an unusual case of LMS of the transverse colon with liver metastasis. The survival of this patient was prolonged by a combined modality therapy involving surgery and chemotherapy.