DOI: 10.36347/sasjm.2022.v08i10.012

Pages: 728-736

Objective: The study aimed to explore the outcome of sleeve gastrectomy and gastric bypass in middle east patients with type 2 diabetes through the assessment of the weight trajectory postoperatively and its effect on the glycaemic control assessed by HbA1c. Where applicable, investigate the impact of sleeve gastrectomy and gastric bypass on the reduction of polypharmacy and postoperative Insulin requirements in patients with type 2 diabetes. Research Design and Methods: PubMed and Science Direct databases were searched. The obtained studies were screened for the title and abstract, followed by full-text reading and retrieved relevant studies. The data was extracted from the relevant papers using a united form according to the inclusion criteria. The articles' quality was assessed and critically appraised, and a narrative synthesis was conducted. Results: Eight studies met the inclusion criteria comprised the final review, and all had positive results. Four articles studied sleeve gastrectomy outcomes, and four compared sleeve gastrectomy and gastric bypass. All studies showed weight reduction postoperatively calculated as BMI, Total Weight Loss, or Excess Weight Loss sustained up to 5 years. The studies which assessed glycaemic control showed improvement of glycaemic parameters, reduction of HBA1C, and some achieved remission among prediabetes and diabetes patients. The review also indicated the reduction and cessation of antidiabetic medications following surgical interventions, which is attributed to achieving diabetes remission. A long-term follow-up cohort with a large sample size revealed that HBA1C reduction was more enunciated and sustained following gastric bypass in patients with diabetes. Conclusion: Sleeve Gastrectomy and Gastric Bypass positively affect type 2 diabetes control among obese adult patients in the Middle East. Both surgical interventions lead to weight reduction and improvement of glycaemic parameters postoperatively up to 5 years .........