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Scholars Journal of Medical Case Reports | Volume-3 | Issue-04
Efficacy Sirulimus and Pathology Report for Angiomyolipoma Patient: A Case Study
Mehrdad Payandeh, Masoud Sadeghi, Edris Sadeghi, Mehrnoush Aeinfar
Published: April 29, 2015 | 160 94
DOI: 10.36347/sjmcr.2015.v03i04.008
Pages: 310-313
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Abstract
Angiomyolipoma (AML) is a benign neo-plasm composed of thick blood vessels, fatty tissue and smooth muscle cells. Herein, we reported a case of revealed diagnosis of AML from kidney and liver features and treated with sirulimus. A 25 year-old woman with a left renal mass incidentally was diagnosed by ultrasound screen for left side of constant abdominal pain. She referred to our cancer center in March 2014. In physical exam of abdomen was normal, without organomegaly. In laboratory exam, the results of urinalysis and other routine blood tests been normal. The decision of urologist at first evaluation with clinical diagnosis of Renal Cell Carcinoma (RCC) was nephrectomy. After nephrectomy in the pathological cross section one encapsulated mass with focal hemorrhage and necrosis were observed. Histopathological examination of the tumor by hematoxylin and eosin staining revealed diagnosis of AML from kidney and liver. We selected her for treatment with mTOR inhibitor of sirulimus (2mg per day). After 3 months, she is in a good condition without any new complaint. During this last three months didn’t have any significant side effects of sirulimus. AML is not a malignancy disorder but is very same to renal cell tumor, and usually is diagnosed after surgery. We must explain this matter that different diagnosis of RCC is multiple and all surgery must know about this matter. This case is metastatic case we must know future details about the pathology.