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Scholars Journal of Applied Medical Sciences | Volume-3 | Issue-01
Evaluation of Status of Salivary Copper in Patients with Oral Leukoplakia
Sham Kishor Kanneppady, Anusha Bhaskar, Prasanna Kumar Rao, Anusha Rangare Lakshman, Ankur Barua, Sowmya Sham Kanneppady
Published: March 28, 2015 |
144
106
DOI: 10.36347/sjams.2015.v03i01.044
Pages: 214-216
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Abstract
The objective of this study was to evaluate the level of copper (Cu) in saliva of patients with oral leukoplakia
(OL) and to compare the values with healthy controls. The study group comprised of 25 clinically diagnosed and
histopathologically confirmed cases of OL; 25 age- and sex-matched controls were also enrolled in the study. The
salivary copper levels were estimated using atomic absorption spectrophotometer. Mean copper level differed
significantly (p<0.05) between the patients and the controls with patients exhibiting higher Cu (137.44±47.03) levels in
contrast to controls who presented lower Cu (112.68±37.95). In conclusion, saliva may be used as a potential diagnostic
tool, which can be employed to evaluate the copper level of OL. Further research is required to identify the exact reason
for increased salivary Cu levels in OL patients by correlating histopathological changes and various tobacco habits in
patients with OL in larger samples.