DOI: 10.36347/sjmcr.2020.v08i05.020

Pages: 570-571

HE LESER-TRELAT SYNDROME (LTS) is a paraneoplastic syndrome characterised by the sudden eruption and rapid increase in size and number of seborrhoeic keratoses as we are reporting in our case [1]. The exact underlying pathogenesis is unknown. Primarily affect the thorax and dorsum, followed by the extremities, face, abdomen, neck and axillaire. It is usually caused by malignancies such as gastrointestinal adenocarcinoma, but also lung, kidney, liver, or pancreatic cancer, mycosis fungoides, Sézary syndrome, and plasmacytoma, have been described in association with this paraneoplastic disorder [3, 4, 5]. After the removal of the internal neoplasm there is a regression of the seborrheic keratoses [2]. LTS should be careful investigated for the existence of an underlying malignancy as illustrated in our case which objectified a tumor of sigmoid.