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Scholars Journal of Applied Medical Sciences | Volume-3 | Issue-01
Paediatric Malignant Soft Tissue Sarcoms: A Clinicopathological Study
Chandrashekhar Thotadamane Nagaraja, Geethalakshmi Ugrappa, Girish Chandrashekara Jarabandi, Rameshbabu K
Published: March 31, 2015 |
138
128
DOI: 10.36347/sjams.2015.v03i01.085
Pages: 436-439
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Abstract
Pediatric soft tissue sarcomas (STSs) are a heterogenous group of malignant tumors originating from primitive
mesenchymal tissue. They account for 7% of all childhood tumors. Risk-based management allows the pediatric
oncologist to determine the risks and benefits of treatment for each patient in order to maximize survival, minimize
morbidity, and improve the quality of life. Thus, accurate histopathological reporting in conjugation with ancillary
methods is needed. We attempted to study the occurrence of soft tissue sarcomas in paediatric population. This study was
under taken to evaluate the incidence and morphological features of malignant soft tissue sarcomas in children of fifteen
years and below. The histopathology slides and paraffin blocks were reviewed. Gross examination was done carefully
noting the size, shape, extent and configuration, nodularity, consistency (solid, cystic or mixed). The sections 3-5 μ thick,
were cut and stained by haematoxylin and eosin in all cases and special stains like PAS, MTS, RT and IHC done where
ever feasible. Thirteen cases were encountered, out of which 9(13.63%) were Rms, 3 (4.54%) were fibrosarcoma and 1
(1.51%) was synovial sarcoma. Case distribution included one in infancy, 2 in 1-5yr, 4 in 5-10yrs and 6 cases in 10-15
yrs age group. In the present study most common site was abdominal wall and the age group was between 10-15 yrs
(46.15%). The mean age being 8 yrs 4mts. Sex ratio of M: F was 1.16:1.