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Scholars Journal of Applied Medical Sciences | Volume-3 | Issue-01
Comparative Study of Cognitive Function in Schizophrenia with and without Obsessive-Compulsive Disorder
Kumar Mahesh, Sharma Pradeep, Goel Nikhil
Published: March 31, 2015 |
150
102
DOI: 10.36347/sjams.2015.v03i01.094
Pages: 478-481
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Abstract
Non-schizophrenic psychopathologies in schizophrenia patients such as, obsessive-compulsive symptoms are
often neglected. But recent studies provide support for the legitimacy of a putative schizo-obsessive diagnostic entity.
Compared to schizophrenia, schizo-obsessive patients have distinct clinical features and and exhibit more deficits in
neurocognitive functioning. The aim and objective of the study was to compare the cognitive function of schizophrenic
patients with and without significant obsessive-compulsive symptoms (OCS). 100 consecutive schizophrenia patients
were taken in the study from psychiatry outpatient department and were assessed using cognitive tests. We then
categorized patients into three groups depending on total Y-BOCS score. Those scoring ≥16 were put in 1st group, 8-15
in 2nd group and <8 in 3rd group. The correlations among symptom profile of patients were analyzed using SPSS17. In
our study, performance on all cognitive domains, was significantly poor among group 1 and 2. There was significant
correlation of Trail A with YBOCS compulsive and total score in group1&2 but not in group3. There was also significant
negative correlation between composite Neurocognitive index (NCCI) and total score of YBOCS in Group1.Finding of
our study suggests that patients with Obsessive compulsive symptoms and schizophrenia were more impaired across a
variety of neuropsychological domains then schizophrenia alone.