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Scholars Journal of Applied Medical Sciences | Volume-3 | Issue-01
The Correlation between Fine Needle Aspiration and Histopathological Diagnosis of the Salivary Gland Lesions of 77 Cases
Sevinç Şahin, Gamze Erkılınç, Sezer Kulaçoğlu
Published: March 31, 2015 |
134
105
DOI: 10.36347/sjams.2015.v03i01.103
Pages: 518-526
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Abstract
The aim of the study is to determine the diagnostic value and accuracy of fine-needle aspiration (FNA) of
salivary gland lesions and to detect the most challenging lesions that cause difficulties cytopathologically. Salivary gland
FNAs and postoperative histopathological diagnosis of 77 cases evaluated in the Department of Pathology at Ankara
Numune Training and Research Hospital in a seven-year period were reviewed and compared retrospectively. Forty-nine
(63.6%) FNAs were diagnosed as benign, 7 (9.1%) were diagnosed as suspicious for malignancy, 2 (2.6%) were
diagnosed as malignant, and 19 (24.7%) were reported as inadequate cytology. Sixty-five (85%) cases were benign, and
12 (15%) were malignant histopathologically. Four cases that were reported as inadequate cytology were diagnosed
histopathologically as malignant. Forty-six FNAs were true negative(TN), three were false negative(FN), five were true
positive(TP), and four were false positive(FP). Specific diagnoses were reported in 39 (67.2%) FNAs. Thirty-two (82%)
of them were verified histopathologically, 7 (18%) were incompatible with the histopathological diagnoses. The rate of
true positivity of FNA was 8.6%, true negativity was 79.3%, false negativity was 5.2%, false positivity was 6.9%,
sensitivity was 62.5%, specificity was 92%, positive predictive value was 55.6%, negative predictive value was 93.9%.
The diagnostic accuracy was estimated as 87.9%. It is noteworthy that sufficiency of the cytological material, the
experience and knowledge of the pathologist, and a comprehensive clinical and radiological findings are crutial for
obtaining a higher rate of diagnostic accuracy in salivary gland FNA.