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Scholars Journal of Applied Medical Sciences | Volume-3 | Issue-02
Malignancy of Thyroid: The 8 Years Institutional Experience
Grace Budhiraja, Monika Gupta, Gurpreet Singh Gill, Paramdeep Singh
Published: April 25, 2015 | 100 70
DOI: 10.36347/sjams.2015.v03i02.001
Pages: 530-537
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Abstract
The aim was to study the epidemiological, pathological parameters and survival of patients with thyroid malignancy. It is a retrospective review of all patients of thyroid malignancy who were managed at our institution. Chisquare test was used for statistical analysis & Kaplan – Meier method was used for calculating survival. A total of 182 patients were included in the study. Parameters evaluated included age, sex, predisposing factors if any, fine needle aspiration cytology diagnosis, nodal status at presentation, intraoperative findings, final histopathological diagnosis, perioperative complications, follow up and survival. Papillary carcinoma was the commonest malignant lesion with a frequency of 87.91% followed by 7.91% for follicular carcinoma, 3.29% medullary carcinoma, 0.89% anaplastic carcinoma. Female predominance was seen (M: F - 5.06:1). The 5 year & 6 year survival rates were 89% and 73 % respectively. The most common postoperative squeal observed was temporary hypocalcaemia seen in 15% patients, followed by permanent hypocalcaemia seen in 8.79%. Temporary recurrent laryngeal nerve palsy was seen in 6.59% patients while permanent recurrent laryngeal nerve paralysis was seen in 4.39% patients. Thyroid malignancies affect all age groups. There was decreased morbidity after lobar or subtotal thyroidectomy as compared to total thyroidectomy.