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Scholars Journal of Applied Medical Sciences | Volume-3 | Issue-02
Comparative Study of the Technique of Limbal Stem Cell Conjunctival Autografting with 0.02% Mitomycin-C and bare sclera excision in the management of Pterygium
Arvind Kumar Morya, Fauzia Rehman Khan
Published: April 26, 2015 | 87 53
DOI: 10.36347/sjams.2015.v03i02.016
Pages: 614-616
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Abstract
The objective is to assess success rate of bare sclera excision and limbal stem cell conjunctival autografting along with intraoperative 0.02% mitomycin-c. Prospective, multicentric , randomized, controlled and comparative intervention study designed with 109 patients which opted two types of surgery for pterygium while visiting the regular OPD over a period of 18 months. 9 patients left the study group on follow up so final study group was of 100 patients. In methodology, Group : Control group (n=50) – Excision of pterygium, leaving bare sclera . Group 2 : Study group(n=50) – Limbal stem cell cojunctival autografting and intraoperative 0.02% Mitomycin-C application after bare sclera excision. All surgeries were performed on outpatient basis by single surgeon using same technique with aim was to assess recurrence rate in two techniques for the management of pterygium. The recurrence rate was 38% in bare sclera excision and only 6% in cases of limbal stem cell conjunctival autografting with intraoperative 0.02% mitomycinc. The recurrence rate was clearly dependent on the type of surgical approach. Limbal stem cell conjunctival autografting and intraoperative application of 0.02% MMC proved to be a far better technique with very low recurrence rate of only 6% whereas bare scleral excision technique resulted in a very high recurrence rate of 38%. The recurrent pterygium cases are better managed only by limbal stem cell conjunctival autografting with 0.02% MMC application.