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Scholars Journal of Applied Medical Sciences | Volume-3 | Issue-02
Clinicopathological Profile of Patients with Lung Cancer Visiting Chest and TB Hospital Amritsar
Navin Pandhi, Balbir Malhotra, Nirmalchand Kajal, Rahul R. Prabhudesai, Nagaraja C.L, Nidhi Mahajan
Published: April 27, 2015 | 47 59
DOI: 10.36347/sjams.2015.v03i02.053
Pages: 802-809
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Abstract
Lung cancer is presently the most common malignant disease in the world. The relative frequency and clinicopathological profile of different histological subtypes of primary lung cancer have been changing in recent years. The present study was conducted to document the clinicopathological and radiological features of patients hospitalized with carcinoma lung to our center. A total of 150 patients with histopathologically proven cases of lung cancer, hospitalized between 2012 and 2014 at a tertiary care Hospital in Punjab, were analyzed. Out of the total 150 histologically proven cases of lung cancer, 73% were males with a male: female ratio was 2.7:1. Most patients were in the age group of 50-70 years with an overall mean age of 59.3 years. 60% of the patients were smokers and all of them were males. Cough (80%) and breathlessness (65%) were the commonest symptoms. Clubbing was the most common finding (50%) followed by vocal cord paralysis (43%). Squamous cell carcinoma (SCC) was the commonest histological type (41%) followed by Adenocarcinoma (36%). SCC most commonly presented in male smokers and adenocarcinoma in females and non-smokers. Most common radiological presentation was solitary pulmonary mass (97%) followed by pleural effusion (60%). Fibreoptic bronchoscopy (42%) and Transthoracic needle aspiration (33%) were the most efficient diagnostic procedures. SCC is the most common histological subtype of primary lung cancer. The relatively increased frequency of adenocarcinoma in our study as compared to other studies from India is probably due to higher proportion of nonsmokers.