An International Publisher for Academic and Scientific Journals
Author Login 
Scholars Journal of Medical Case Reports | Volume-8 | Issue-06
Treatment-Resistant Actinomycosis Reveals Concomitant Systemic Vasculitis
Faris Althubaiti, Sylvain Godreuil, Muriel Lalande, Aurelia Carbasse, Yassine al Tabaa, Hélène Vernhet, Vanessa Szableski, Valerie Costes, Eric Jeziorski
Published: June 18, 2020 | 177 122
DOI: 10.36347/sjmcr.2020.v08i06.008
Pages: 623-626
Downloads
Abstract
Takayasu Arteritis (TA) is a granulomatous systemic vasculitis that mainly involves the aorta and its large branches. Its etiology is unknown; however, several triggering factors have been reported. Infectious agents are thought to have a role in the disease pathogenesis mainly mycobacterium tuberculosis. Early diagnosis is sometimes challenging in the absence of adequately sensitive biomarkers and the intermittent nature of this disease. We present here a thirteen-year-old girl who fell down on her chin and fractured her 21st tooth, presented to us with posttraumatic febrile illness and unilateral headaches. A diagnosis of posttraumatic left mandibular osteitis was done initially supported by clinico-radiological and histopathological findings. Due to treatment resistance and appearance of other clinical features mainly “Arterial hypertension and prominent carotid pulsations” the diagnosis of TA was considered. Treatment by corticotherapy was initiated but because of corticodependence, infliximab and methotrexate were introduced and permitted us to stop steroid therapy, without any flare or new attempt 4 years after diagnosis. We suggest that these rare granulomatous diseases can co-occur and should be evoked in atypically evolving cases.