DOI: 10.36347/sjams.2015.v03i02.068

Pages: 878-883

Klebsiella spp. is ubiquitous in nature. They inhabit the environment and intestinal tract of humans and animals. Klebsiella spp causes variety of healthcare associated infections including pneumonia, urinary tract infections, blood stream infections, surgical wound infections, peritonitis, septicaemia and meningitis. Klebsiella are highly drug resistant bacilli causing significant morbidity and mortality. Foregoing study aims at isolation of Klebsiella spp. from different clinical specimens and their antibiogram, which would enable formulation of appropriate antimicrobial policy for patients suffering from Klebsiella infection. A total of 1957 various clinical samples at Microbiology diagnostic laboratory of KVG Medical College & Hospital, Sullia were processed. A total of 100 strains of Klebsiella spp. isolated were identified by standard procedures. Antibiotic susceptibility testing was done by Kirby-Bauer disc diffusion method and interpreted as per CLSI guidelines. A total of 100 Klebsiella spp were isolated from 1957 clinical samples including sputum, urine, blood, wound swabs and various aspirates. 79% were Klebsiella pneumoniae and 21% were Klebsiella oxytoca. The highest percentage of Klebsiella spp (40%) were isolated from pus sample. The isolates were 100% sensitive to imipenem and showed sensitivity to fourth generation cephalosporin cefepime (77%), amikacin (74%) and gentamicin (70%). Isolates showed high resistance to ampicillin (89%), followed by aztreonam (83%) and piperacillin/ tazobactam (67%). Among the third generation cephalosporins tested Klebsiella isolates showed high resistance to cefotaxime (65%).