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Scholars Journal of Applied Medical Sciences | Volume-3 | Issue-02
Diagnostic Value of Ferroxidase Activity of Ceruloplasmin in Extra Pulmonary Tuberculosis
G. Anuradha, Mythili
Published: April 28, 2015 | 53 59
DOI: 10.36347/sjams.2015.v03i02.076
Pages: 919-921
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Abstract
The aim of this study is to assess the diagnostic level of Ferroxidase activity of ceruloplasmin in tuberculousserosal effusion. The study was carried out on 50 patients suffering from tuberculous pleural and peritoneal effusion and 50 patients suffering from non- tuberculous pleural and peritoneal effusion. Mean ± SD of ferroxidase in tuberculous pleural effusion was 1042 ± 112 IU/L and the sensitivity and specificity was 100% and 95% respectively. Mean ± SD of ferroxidase in tuberculous peritoneal effusion was 968 ± 94 IU/L and sensitivity and specificity was 100% and 94% respectively. Serosal fluid ferroxidase estimation is a simple and rapid test with high degree of sensitivity and specificity. Hence Ferroxidase activity of ceruloplasmin may be used as a surrogate marker for tuberculousserosal effusion.