DOI: 10.36347/sjds.2015.v02i02.021

Pages: 195-198

Abstract: Oral infection such as tooth caries and periodontal desease are the most commond bacterial infection in human. The main cause of periodontal disease is microorganisms that colonize and attached to the tooth surface around the gingival margin. Streptococcus mutans is the first bacteria that forms colonies and become the initiator of the other bacteriato do so. The left bacteria colonies may change to be plaque layer and causes an inflammatory reaction, may lead to tissue damage. Propolis is a natural substance, well known its benefits in dentistry. The type of propolis varies depending on the area or location and type of honey bees that produce it. Propolis is also expected to inhibit Streptococcus mutans that cause periodontal disease.: The aim of the study is determine the inhibition zone of propolis extract from South Sulawesi on Streptococcus mutans. Inhibition test was performed by the agar diffusion method using propolis test materials, provided in a concentrationof 2.5%, 5%, and 10% as well as negative control. Inhibition zone was measured after 24 hours incubation. Concentration has effect that causing significant difference in inhibition of the change in concentration of propolis (p<0.005). The use of different solvents in the extraction process also has an influence on the inhibition of propolis or there is a significant difference between the propolis extracted with hexane solution (fat-free propolis) and 70% of propolis solution (p<0.005).The interaction between the type of solvent with a concentration on its effect on the inhibition of propolis also showed a significant difference (p<0.005). South Sulawesi Propolis has inhibitory effect on Streptococcus mutans especially those was dissolved in70% ethanol solution and also influenced by the level of concentration.