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Scholars Journal of Applied Medical Sciences | Volume-3 | Issue-02
The Sensitivity of Cytology in the Differential Diagnosis of Ascites among Adult Nigerians in a Tertiary Health Institution
Ekpe EEL, Omotoso AJ
Published: April 28, 2015 |
139
118
DOI: 10.36347/sjams.2015.v03i02.087
Pages: 969-972
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Abstract
Ascites is a common clinical problem confronting physicians and is commonly encountered in many patients
with liver diseases, cardiac failure, renal diseases, and malignancies. Currently, differentiation of the fluid by laboratory
analysis into malignant and non-malignant ascites has not been fully achieved yet. The aim was to assess the diagnostic
accuracy of cytology in the differential diagnosis of ascites. A total of seventy five unselected patients with ascites were
studied. Thirty seven of them had malignancy-related ascites (7 males, 30 females), while 38 had non-malignant ascites
(18 males, 20 females). Cytology was done for all ascitic fluid samples collected from these patients. Cytology yielded
an accuracy of 78.7% and a sensitivity of 56.8%. Hence, it is found that cytology alone may not be too useful in
differentiating malignant from non-malignant ascites as its sensitivity is low and so other biochemical parameters may be
needed to supplement cytology in the differential diagnosis of ascites.