DOI: 10.36347/sjams.2015.v03i02.093

Pages: 995-999

Postoperative wound infections have been an important cause of morbidity and cost burden for the patients and also the determination of antimicrobial resistant strains makes the clinicians a hectic role in management. The main objective of this investigation is to find out the ESBL producing gram negative bacilli in postoperative wound infections in various specialities. The methodology comprised the incorporation of the pus swabs and aspirates from 108 postoperative wound infection cases. The bacterial etiology was identified and antimicrobial susceptibility test was done. All gram negative bacilli resistant to 3rd generation cephalosporins were subjected to ESBL detection by double disk synergy test, E test and ESBL screening agar test. Of the 108 patients, various bacterial pathogens were recovered from 94 patients (87%). Monomicrobial and polymicrobial infection was observed in 62.8% and 37.2% patients respectively. A total of 134 isolates were recovered from 94 patients with postoperative wound infections (38.8% gram negative and 61.2% gram positive). The antibiotic sensitivity test was performed using a battery of antibiotics and ESBL production among 44.2% isolates was observed. ESBL production was detected in 47.4% of Escherichia coli and 50% of Klebsiella pneumoniae. Further, managing the infection with precise empirical treatment, policy of reviewing prescription patterns and continuous monitoring of resistance patterns of the etiological agents can help the prevention of post operative infections