DOI: 10.36347/sjds.2015.v02i06.003

Pages: 355-362

Abstract: Platelet rich plasma (PRP) is one of the new innovations of surgery today and is a new approach to tissue regeneration. It is helpful in both hard and soft tissue healing. PRP is derived from autologous blood and is a reservoir of various growth factors which are important for tissue repair. In the field of surgery, it tends to give an added advantage by both reducing bleeding and also helping in wound healing or tissue repair. Various studies have been carried out on humans to show the application and benefits of PRP in dentistry (especially enhancing healing of extraction sockets, implant surgery, periodontal surgery, bone regeneration etc). The use of PRP has also been proposed in the treatment of bisphosphonate- related osteoradionecrosis of the jaw (BRONJ), as a better treatment modality as compared to the conventional methods. The main aim of this short narrative review is to 1) create awareness about what is PRP, 2) its methods of preparation, 3) various clinical applications and its promising results. As PRP is an autologous preparation, it is free from the potential risks associated with any other grafts. It definitely holds a promise in near future. However, more RCTs are still required to support its evidence. In this review, articles were searched online in recent journals by using certain relevant keywords regarding the clinical applications of PRP.