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Scholars Journal of Applied Medical Sciences | Volume-3 | Issue-03
Co-morbidities in Coronary Artery Disease Post-menopausal Women: Data from Southern Italy
Marco Matteo Ciccone, Francesca Cortese, Pietro Scicchitano, Annapaola Zito, Michele Gesualdo, Maria Maiello, Pasquale Palmiero
Published: May 26, 2015 |
163
139
DOI: 10.36347/sjams.2015.v03i03.022
Pages: 1143-1148
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Abstract
The aim of our study was to determine the “real-world” prevalence of co-morbidities in a Southern Italian
population of postmenopausal women with or without coronary artery disease (CAD) who come to the emergency
department for chest pain and suspicion of coronary involvement. 6535 post-menopausal women (mean age: 64 + 9
years) were enrolled in the study. On the base of results of coronary angiography we recognized CAD-group and CADfree group. Congestive heart failure (CHF), stroke and chronic lower respiratory tract diseases (CLRTD), hypertension,
diabetes, dizziness or syncope, chronic renal failure, urinary incontinence, >4 medications and/or Warfarin use were
detected. Results of our study show that 528 (8.1%) women suffered from CAD. Compared to CAD free group, women
with CAD have higher prevalence of CHF (9.1% vs. 1.6%, p=0.02), stroke (6% vs. 0.6%, p<0.01) and CLTRD (6.5% vs.
5.4%, p=0.04). Moreover in CAD population, we found significant higher percentages of patients with low GFR (0.9%
vs. 0.6%, p=0.02) and Warfarin use (2.3% vs. 2%, p<0.01) than in CAD-free one. The two group did not differ about
hypertension, diabetes mellitus, >4 medications use and urinary incontinence (p=ns). Among postmenopausal women
with chest pain and suspicion of coronary involvement, those with CAD showed higher co-morbidities percentage than
CAD-free. The overall clinical condition should be considered in order to ameliorate care, improve quality of life, reduce
morbidity/mortality.