DOI: 10.36347/sjams.2015.v03i03.042

Pages: 1259-1265

Stroke is an abrupt onset of a neurological deficit that is attributable to a focal vascular cause. It is encountered quite frequently in clinical practice. The role of circulating lipids and lipoproteins in the pathogenesis of young stroke remains uncertain even after decades of research. Diabetes is an important cause for dyslipidaemia. In this present study an attempt is made to evaluate the association between serum lipids and young non diabetic stroke patients. This study was conducted on 30 patients of young nondiabetic stroke patients. Our study included 25 patients of Ischemic stroke, 5 patients of Hemorrhagic stroke and 30 age and sex matched healthy controls. Duration of study was from September 2010 to October 2013. Patients with cerebrovascular diseases associated with diabetes, head injury, pregnancy, puerperium, infections, hepatic encephalopathy, uraemic encephalopathy, nephrotic syndrome and patients on lipid lowering drugs were excluded. Venous blood was collected for the estimation of serum total cholesterol, triglycerides, LDL-C, HDL-C, VLDL-C by standard methods. Most common age group in our study was 37-45 years comprising 53.33% of cases. Males (76.7%) were more than females (23.3%) 63.41% of patients had elevated total cholesterol (mean 210.33 + 71.61). 70% had elevated triglycerides (mean 184.93 + 74.49), High LDL-C value (mean 131.78 + 61.49) was seen in 46.7% of cases. The HDL-C levels (mean 44.71 + 17.43) was seen in 43.3% of cases, High VLDL-C value (mean 33.94+ 15.18) was seen in 56.7% of cases. The levels of total cholesterol, Triglycerides, LDL-C, TC/HDLC, LDL-C/ HDL-C in cases were significantly raised when compared to control group (p<0.001).