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Scholars Journal of Applied Medical Sciences | Volume-3 | Issue-03
Clinical Features of Congenital Anosmia
Nobuko Makino, Shinji Makino
Published: May 27, 2015 |
135
119
DOI: 10.36347/sjams.2015.v03i03.057
Pages: 1323-1325
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Abstract
The objective of the study was to evaluate the clinical features of congenital anosmia. We retrospectively
analyzed 205 patients at our hospital for olfactory disturbances over a 4-year period. The overall prevalence of congenital
anosmia was found to be 3.4% (7/205). Magnetic resonance imaging of the brain revealed the absence of the olfactory
bulbs, tracts, and hypoplasia of the olfactory sulci in all patients. Two patients who had hypogonadotropic hypogonadism
were diagnosed with Kallmann syndrome of the patients who complained of olfactory disturbances, the prevalence of
congenital anosmia was found to be 3.4%. These results may aid in explaining clinically rare conditions. We emphasize
that young patients should be carefully observed for the development of secondary sex characteristics, and hormone
replacement therapy should be considered in patients of a fertile age.