DOI: 10.36347/sjams.2015.v03i04.017

Pages: 1694-1697

Sydnones are the mesoionic compounds having wide range of biological activities. Structural modifications at various positions have provided different class of sydnones, thiazolo-thiourea sydnones are one among them. Nowadays Greenfield chemistry revolves around the design and development of chemical compounds in feasible economical and nonhazardous way. Ten different thiazolo thiourea sydnones compounds were tested for their antibacterial activity. They were tested on Staphylococcus aureus, Escherichia coli, Proteus vulgaris and Pseudomonas pyocyneous using agar well method. Out of the ten different Thiazolo thiourea sydnones derivatives compounds 2, 3 and 10 showed promising results others also had some antibacterial activity. It can be concluded from the above study that Thiazolo thiourea compounds have antibacterial property.