DOI: 10.36347/sjds.2016.v03i04.004

Pages: 121-123

Abstract: Ectodermal dysplasia(ED) is defined as a disorder involving structures developing from the ectoderm skin, hair, teeth and sweat glands as well as structures that interact with the ectoderm. These types of ectodermal dysplasias are heritable or genetic disorders. In few cases, it is possible for a child to be the first person in his or her family to be affected by an ectodermal dysplasia. The EDA, EDAR, and EDARADD genes are responsible for cause hypohidrotic ectodermal dysplasia due to mutation in genes mentioned above. The genes EDA, EDAR, and EDARADD provide instructions for making proteins that work together during embryonic development. These proteins form part of a signaling pathway that is critical for the interaction between two germal cell layers, the ectoderm and the mesoderm. In the early embryo, these cell layers form the basis for many of the body's organs and tissues. The interactions between ectoderm-mesoderm are essential for the formation of several structures that arise from the ectoderm.A male patient aged 15 yrs. old (with dental opd registration no.4634/16) reported to the dental outdoor of IGIMS, Patna with complains of yellowish teeth and difficulty in chewing. His mother gave the history that she had twin baby one died at the time of birth and the second one has this problems. On examination his all teeth were erupted (except third molars) with malformed teeth structures and yellowish in colors. There are no cures for ectodermal dysplasias, but many treatments are available to address the symptoms. Second case of a young male child patient aged 05 yrs. old (with dental opd registration no.44460/16) reported to the dental outdoor of IGIMS, Patna, Bihar with complains of teeth are not erupting. The cases are treated symptomatically and long term Prosthodontic treatment plan was advised in case of for second case.