DOI: 10.36347/sjds.2016.v03i10.005

Pages: 290-295

Abstract: Chronic exposure to periodontal bacteria and their products thought to be responsible for the pathogenesis of systemic diseases. The aim is to evaluate effect of non- surgical periodontal therapy on liver function in systemically healthy chronic periodontitis (CP) subjects. The study includes 50 CP subjects with age group of 35- 60 years selected from the OPD of department of periodontology TKDC and research center RC, Kolhapur. Subjects were equally divided into test (TG) and control group (CG). Liver function test- AST & ALT were checked at baseline and at 1 month after treatment. Clinical examination includes PI, GI, SBI, PD, CAL. Comparison between group I and group II for all the measures of periodontal parameters and AST levels were analyzed by applying Student t test. A statistically significant difference (P<0.05) between mean PI, GI PD, CAL, AST & ALT levels at baseline and after 1–months of initial therapy was obtained, suggestive of a significant decrease in mean PI, GI, PD, CAL, AST & ALT levels in TG after therapy as compared to that of baseline. There is a correlation between liver markers and periodontitis suggesting that AST and ALT levels decreases when periodontal status improves.