DOI: 10.36347/sjds.2016.v03i12.002

Pages: 317-322

Abstract: Ever since its introduction Ultrasound (US) has been evolved remarkably to present features with better promises and reached new horizons, often one such turnover from diagnostic to therapeutic application leads in introduction of micro bubbles. It is a new innovative method with minimal invasive procedure of drug and gene delivery to target sites with a specific targeted ligand on micro bubbles. Micro bubbles are small air filled central core with flexible or rigid shell composed of albumin or lipid or polymer. Micro bubbles on application of US beam rapidly contract and expand in response to pressure change of sound waves. Micro bubbles upon ionization of sufficiently intense pressure will cavitat, sonoporation employs the cavitation of micro bubbles to enhance the delivery of drug and genes, Cavitation with micro bubbles can be used to dissolve the blood clots or drug delivery. Aim of this review is to highlight many such diagnostic and therapeutic application of Ultrasonography mediated micro bubbles.