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Scholars Journal of Applied Medical Sciences | Volume-3 | Issue-05
Comparative Study of Neostigmine as an Adjuvent with Ropivacine during Postoperative Analgesia in Children
Kumar R, Mahta RK, Trivedi S
Published: Aug. 27, 2015 |
176
115
DOI: 10.36347/sjams.2015.v03i05.012
Pages: 1861-1866
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Abstract
In order to evaluate the postoperative analgesic effect of caudal administration of neostigmine with or without
ropivacine, 120 children of aged 2-10 years, who underwent elective infraumblical surgeries, were studied. The children
were randomly divided into two groups: Group A (n -60) received 0.2% Ropivacaine 0.5 ml/kg, and Group B (n-60)
received 0.2% Ropivacaine 0.5 ml/kg with 2µg/kg Neostigmine via the caudal route. Assessment of analgesia in post
operative period done by Modified Children’s Hospital of Eastern Ontario Pain Scale (MCHEOPS) for a period of 24 hrs
the pain score was significantly lower in Group B as compared to Group A. The mean duration of analgesia in Group A
patients was 440±25 minutes, and Group B patients were 690±31 minutes. There are no significant side effects seen in
the patients. In the conclusion the caudal administration of Ropivacine with Neostigmine resulted in prolonged duration
of analgesia as compared to Ropivacaine alone.