DOI: 10.36347/sjams.2015.v03i05.051

Pages: 2058-2063

Diabetes is often associated with metabolic syndrome that is high blood pressure and abnormal lipid profile. Micronutrients mostly refer to vitamins and minerals. Micronutrients mainly exert their function as enzyme cofactors and transcription factors thus controlling the metabolic pathways. Metabolic syndrome is often characterized by various other clinical features like disturbance in glucose and insulin metabolism, obesity and abdominal fat distribution. Aim of the study was to determine the difference in serum Zinc, Copper, Magnesium, ceruloplasmin and ferritin levels in diabetic patients and to assess if there is a correlation between the micronutrients and metabolic parameters. The study was conducted in the Departments of Biochemistry and Medicine, Kasturba Medical College, Manipal. Serum Zinc, Copper and Magnesium were estimated using quantitative colorimetric assay kits. Fasting blood sugar was analyzed using cobas 912 and lipid profile and serum ferritin was estimated using cobas 6000 auto analyzers. Serum Ceruloplasmin were estimated by manual method. There is a statistically significant increase in serum Zinc level in the diabetic group (p=0.003) compared to controls. Fasting blood glucose varied among cases and controls significantly (p<0.001). However there was no statistically significant difference among the two groups in any of the other parameters. Also no statistically significant correlation between the minerals and metabolic parameters was obtained in either of the groups.