DOI: 10.36347/sjmcr.2020.v08i08.008

Pages: 774-777

Motor evoked potentials (MEPs) monitoring has been applied for an early detection of the intraoperative neurologic injury. As a landmark, baseline MEPs should be accurately measured before surgical interventions. Many anesthetics, especially neuromuscular blocking agents can attenuate MEPs, and residual neuromuscular blocking effects can interfere with accurate interpretation of MEPs. Therefore, it should be antagonized completely and rapidly before measuring the baseline MEPs. We evaluated the efficacy of sugammadex in antagonizing the residual effect of rocuronium for 10 patients. In all patients with administration of sugammadex dose of 2-4 mg/kg, neuromuscular blockade was completely reversed within 5 minutes after administration of sugammadex, even in the case with deep neuromuscular block (TOF count 0). Appropriate MEPs amplitudes were measured during the surgery after reversal, with previous mild, moderate even deep neuromuscular blockade depths. The residual effect of neuromuscular blockade before MEPs monitoring in spine surgery should be completely reversed, and the sugammadex showed a good efficacy in neuromuscular blockade reversal.