DOI: 10.36347/sjams.2015.v03i05.067

Pages: 2128-2131

To assess and compare the significance of serum iron and TIBC in patients with chronic liver disease and also comparision between alcoholic and non alcoholic CLD. The study was conducted J.A.Group of Hospital during the period of June 2013 to November 2014 and about 100 patients of chronic liver disease were selected in random from patients coming to department of general medicine OPD and ward patients. The study of 100 patients with chronic liver diseases, which were examined for frequency and correlation between elevated liver enzymes, haematological parameters, ultrasound diagnosed features of chronic liver disease and indices of iron. Mean TIBC in Child Pugh class C was 276.03 + 33.48 (p value 0.00001). TIBC was higher significantly in non alcoholic CLD patients 335.47±35.91 (p value <0.00001).Mean serum iron in Child Pugh class C was 129.03 + 51.53 which was significantly higher than rest of group. Child Pugh class A has serum iron mean 82.33 + 26.59. Serum iron was significantly higher in alcoholic CLD patients 143.73±16.21 (p value <0.0001). Serum iron increased and TIBC decreased with increasing disease severity according to Child Pugh score. So there is good correlation of severity of CLD with serum iron and TIBC. In our study these changes are more in alcoholic group.