DOI: 10.36347/sjams.2015.v03i05.069

Pages: 2135-2138

Tuberculosis has become the most important communicable disease in the world, with over 8 million cases of pulmonary tuberculosis occurring each year, 95% of which are in developing countries. Sputum smear examination is an important modality of diagnosis of pulmonary tuberculosis Smear negativity with clinical and radiological features of pulmonary tuberculosis is a common problem, sputum induction with 3% hypertonic saline helps in obtaining adequate yield of sputum and more chances of smear positivity. To find out the yield in diagnosis of smear negative suspected pulmonary tuberculosis by sputum induction using 3% hypertonic saline nebulisation. The study was carried out in Sri Adhi chunchungiri institute of medical science the study period was of 18 months from August 2011 to February 2013. 50 patients admitted with clinical and radiological features suggestive of pulmonary tuberculosis was studied and investigations like blood routine, including ESR, ECG, chest X-ray, sputum induction, smear study by Zeil Neilson staining and sputum culture were be done to all the cases after sputum induction using 3% hypertonic saline nebulisation. Among 50 cases, 30(60%) cases were in the age group of 30 –60 years, 34(68%) cases were Males and 16 (32%) cases were females. 19 (38%) cases had no other associated diseases and 31(62%) cases had associated diseases like diabetes mellitus 12(24%), hypertension-15(30%), HIV-1(2%), IHD-2(4%), AF-1(2%). Cutaneous stigmata like lymph adenopathy, erythema nodosum, and lupus vulgaris were present in 10(20%) cases and absent 40(80%) cases.