DOI: 10.36347/sjams.2015.v03i05.070

Pages: 2139-2145

Many studies have sought to determine factors for predicting cardiovascular diseases (CVD), and it is already known that metabolic syndrome increases the incidence and mortality rate of CVD. The purpose of this study was to investigate the correlation between the three highs, which are hypertension, hyperglycemia, and hyperlipidemia on tenyear risk of CVD for sex difference. A cross-sectional study design was adopted for the periods from August 2011 to December 2013. Subjects were people who participated in an adult health check at a regional hospital in Pingtung City in Southern Taiwan. The 10-year cardiovascular risk assessment of the Framingham Heart Study was used to calculate the risk, with ≦10% indicating low risk, 11~20% medium risk, and >20% high risk. Multiple logistic regression analysis was used to evaluate the effect that the three highs have on the 10-year risk of patients with cardiovascular diseases. The results indicated that men aged 65 or older, smoke, drink, or chew betel nut had a significantly higher 10-year risk for CVD; those with metabolic syndrome and its components also had a significantly higher 10-year risk for CVD. Comparison of men and women found that those suffering from more of these conditions had a significantly higher 10- year risk of CVD. Logistic regression analysis for males indicated the 10-year risk of CVD increased as hypertension, hyperglycemia, and hyperlipidemia increased and the odds ratios were 3.44, 8.13, and 16.64, respectively. In conclusion, hypertension, hyperglycemia, and hyperlipidemia are risk factor affecting the 10-year risk for CVD for both men and women and men have a higher risk if they suffer from more than one of these conditions. Strict and proactive treatment and control is necessary to reduce the incidence of cardiovascular disease.