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Scholars Journal of Applied Medical Sciences | Volume-3 | Issue-06
Comparison of Serum Zinc Level in Patients with Simple Febrile Seizure versus Acute Febrile Illness
Vidyasagar V, Venugopal BL, Darshan MS
Published: Sept. 26, 2015 |
169
128
DOI: 10.36347/sjams.2015.v03i06.012
Pages: 2210-2219
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Abstract
Febrile seizure is a common illness in children in the age group of 6 months to 5 years. The role of
microelements like zinc has been studied in febrile seizures previously, but fever is known to reduce serum zinc levels.
The present study aims to compare serum zinc in children with simple febrile seizures and acute febrile illness. A
hospital based comparative study, consisting of infants and children aged between 6 months to 5 years, 80 children each
in two groups i.e. group A and group B shall be included for the study. Group-A: children with simple febrile seizures
aged between 6 months to 5 years. Group –B: children with acute febrile illness aged between 6 months to 5 years.
Serum Zinc estimation done in both groups by colorimetric method and compared using various statistical tests. Mean
serum Zinc level was lower in group A (59.93µgm/dl) compared to group B (69.99µgm/dl), and was a statistically
significant (p=0.001). Serum zinc level was lower in children with simple febrile seizures as compared to children with
acute febrile illness.