DOI: 10.36347/sasjm

Pages: 103-111

In this study, the effect of Esbiothrin-based mosquito coil exposure on the ovary of Wistar rats where studied. Twenty (20) Wistar rats (8 to 10 weeks old) weighing 120-130 g were divided into four groups (A, B, C and D) of five rats each. The rats in group A served as the negative control group while the rats in B, C and D were exposed via whole body inhalation to the commercially available mosquito coil smoke for 8 hours (7am-3pm), 12 hours (7am-7pm) and 16 hours (7am-11pm) every day for 3 weeks respectively. The rats were sacrificed after 21 days using cervical dislocation. There was a significant (p<0.05) decrease in primary follicles, secondary follicles, graffian follicles, the level of Follicle stimulating hormone, Luteinizing hormone and Progesterone when compared to models in control group. Also, there was a significant (p<0.05) increase in the level of Malondiadehyde and atretic follicles when compared to animals in the control group. Taken together therefore, it was concluded that Esbiothrin-based mosquito coil is toxic to the ovary of female Wistar rat.