DOI: 10.36347/sasjm

Pages: 116-120

Chronic suppurative otitis media (CSOM) is one of the common otological problems in our community and atticoantral type is associated with increased incidence of intracranial and extracranial complications. The aim of this study is to determine the type and pattern of drug susceptibility of the pathogenic microorganisms causing atticoantral disease, which could lead to better therapeutic decisions, thereby reducing the potential risks of complications. Total 42 Patients with persistent otorrhea for more than 3 months with atticoantral type of chronic otitis media were selected. The exudates were collected under sterile conditions and inoculated onto culture media; bacterial growth and drug sensitivity pattern were studied. This study analyzes the causal organisms and their sensitivity to various antimicrobial agents. Most frequently isolated agents were Pseudomonas aeruginosa (25.4%) followed by proteus mirabilis (23.7%) and Staphylococcus aureus (6.8%) while other organisms such as Providencia species, Escherichia coli, Klebsella, Enterobacter and Citrobacter species were the less commonly involved organisms. Drug sensitivities pattern of P. aeruginosa showed that ciprofloxacin was active against the majority of isolates (93.9%) followed by ceftazidime 86.2% and amikacin 76.2%. Whereas the sensitivity of P. mirabilis was 100% to ceftazidime and ciprofloxacin, 95.2% to amoxil/clavulanic acid and amikacin. All (100%) of the Staphylococcus isolates were sensitive to vancomycin, 96.2% to ciprofloxacin and 93.1% were sensitive to amoxil/clavulanic acid. Continuous and periodic evaluation of microbiological pattern and drug sensitivity of atticoantral CSOM is necessary to decrease the potential risks of complications by early institution of appropriate systemic and topical antibiotic alongside mastoid exploration.